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1

Rilotumumab in combination with epirubicin, cisplatin, and capecitabine as first-line treatment for gastric or oesophagogastric junction adenocarcinoma: an open-label, dose de-escalation phase 1b study and a double-blind, randomised phase 2 study

Iveson, Timothy, Donehower, Ross C, Davidenko, Irina, Tjulandin, Sergey, Deptala, Andrzej, Harrison, Mark, Nirni, Somanath, Lakshmaiah, Kuntegowdanahalli, Thomas, Anne, Jiang, Yizhou, Zhu, Min, Tang,

Journal:

The Lancet Oncology

Year:

2014

Language:

english

File:

PDF, 339 KB

english, 2014

2

Long term follow-up of women treated with 16-week, dose-intensive adjuvant chemotherapy for high risk breast carcinoma

Bahar Mikhak, Marianna Zahurak, Martin D. Abeloff, John H. Fetting, Nancy E. Davidson, Ross C. Donehower, William Waterfield, M. John Kennedy

Journal:

Year:

1999

Language:

english

File:

PDF, 84 KB

english, 1999

3

Taxol toxicity. Epithelial necrosis in the gastrointestinal tract associated with polymerized microtubule accumulation and mitotic arrest

Ralph H. Hruban, John H. Yardley, Ross C. Donehower, John K. Boitnott

Journal:

Year:

1989

Language:

english

File:

PDF, 825 KB

english, 1989

4

Peripheral neuropathy from taxol and cisplatin combination chemotherapy: Clinical and electrophysiological studies

Dr. Vinay Chaudhry, Eric K. Rowinsky, Susan E. Sartorius, Ross C. Donehower, David R. Cornblath

Journal:

Annals of Neurology

Year:

1994

Language:

english

File:

PDF, 711 KB

english, 1994

5

Phase II study of N-methylformamide, spirogermanium, and 4-demethoxydaunorubicin in the treatment of non-small cell lung cancer (EST 3583): An Eastern cooperative oncology group study

David S. Ettinger, Dianne M. Finkelstein, Ross C. Donehower, Alex Y. C. Chang, Michael Green, Ronald Blum, Richard G. Hahn, John C. Ruckdeschel

Journal:

Pediatric Blood & Cancer

Year:

1989

Language:

english

File:

PDF, 407 KB

english, 1989

6

Adjuvant Concurrent Chemoradiation for Adenocarcinoma of the Distal Common Bile Duct

Michael A. Hughes, Deborah A. Frassica, Charles J. Yeo, Taylor S. Riall, Keith D. Lillemoe, John L. Cameron, Ross C. Donehower, Daniel A. Laheru, Ralph H. Hruban, Ross A. Abrams

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2007

Language:

english

File:

PDF, 251 KB

english, 2007

7

Validation and implementation of a liquid chromatography/tandem mass spectrometry assay to quantitate ON 01910.Na, a mitotic progression modulator, in human plasma

Jing Li, Ming Zhao, Antonio Jimeno, Ping He, M.V. Ramana Reddy, Manuel Hidalgo, Ross C. Donehower, Michelle A. Rudek

Journal:

Journal of Chromatography B

Year:

2007

Language:

english

File:

PDF, 213 KB

english, 2007

8

Intensified adjuvant combined modality therapy for resected periampullary adenocarcinoma: acceptable toxicity and suggestion of improved 1-year disease-free survival

Anuradha Chakravarthy, Ross A Abrams, Charles J Yeo, Larry T Korman, Ross C Donehower, Ralph H Hruban, Marianna L Zahurek, Louise B Grochow, Seamus O’Reilly, Herbert Hurwitz, Elizabeth M Jaffee, Keith

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2000

Language:

english

File:

PDF, 136 KB

english, 2000

9

The Clinical Development of Paclitaxel: A Successful Collaboration of Academia, Industry and the National Cancer Institute

Dr. Ross C. Donehower

Journal:

Year:

1996

Language:

english

File:

PDF, 23 KB

english, 1996

10

Phase II Studies

M. John Kennedy, Ross C. Donehower, Louise B. Grochow, David S. Ettinger, John H. Fetting, Martin D. Abeloff

Journal:

Investigational New Drugs

Year:

1990

Language:

english

File:

PDF, 451 KB

english, 1990

11

Assessment of N-methylformamide (NMF) administered orally on a three times weekly schedule: a phase I study

Eric K. Rowinsky, Louise B. Grochow, Alexander Hantel, David S. Ettinger, Barbara L. Vito, Ross C. Donehower

Journal:

Investigational New Drugs

Year:

1989

Language:

english

File:

PDF, 717 KB

english, 1989

12

Evaluation of weekly escalating doses of dichloromethotrexate in patients with hepatocellular carcinoma and other solid tumors

William J. Tester, Ross C. Donehower, Joyce L. Eddy, Charles E. Myers, Daniel C. Ihde

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1982

Language:

english

File:

PDF, 525 KB

english, 1982

13

A phase I trial of trimetrexate glucuronate (NSC 352122) given every 3 weeks: clinical pharmacology and pharmacodynamics

Louise B. Grochow, Dennis A. Noe, David S. Ettinger, Ross C. Donehower

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1989

Language:

english

File:

PDF, 694 KB

english, 1989

14

Phase I and pharmacokinetic study of UCN-01 in combination with irinotecan in patients with solid tumors

Antonio Jimeno, Michelle A. Rudek, Thomas Purcell, Daniel A. Laheru, Wells A. Messersmith, Janet Dancey, Michael A. Carducci, Sharyn D. Baker, Manuel Hidalgo, Ross C. Donehower

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2008

Language:

english

File:

PDF, 438 KB

english, 2008

15

Phase I trial of weekly trabectedin (ET-743) and gemcitabine in patients with advanced solid tumors

Wells A. Messersmith, Antonio Jimeno, David Ettinger, Dan Laheru, Julie Brahmer, Dina Lansey, Yasmin Khan, Ross C. Donehower, Yusri Elsayed, Peter Zannikos, Manuel Hidalgo

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2008

Language:

english

File:

PDF, 316 KB

english, 2008

16

A multicenter analysis of GTX chemotherapy in patients with locally advanced and metastatic pancreatic adenocarcinoma

Ana De Jesus-Acosta, George R. Oliver, Amanda Blackford, Katharine Kinsman, Edna I. Flores, Lalan S. Wilfong, Lei Zheng, Ross C. Donehower, David Cosgrove, Daniel Laheru, Dung T. Le, Ki Chung, Luis A.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2012

Language:

english

File:

PDF, 361 KB

english, 2012

17

The effects of food and divided dosing on the bioavailability of oral vinorelbine

E. K. Rowinsky, V. Sol Lucas, A.-L. Y. Hsieh, William A. Wargin, John A. Hohneker, Barbara Lubejko, Susan E. Sartorius, Ross C. Donehower

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1996

Language:

english

File:

PDF, 605 KB

english, 1996

18

Phase I trial of the matrix metalloproteinase inhibitor BAY12-9566 in patients with advanced solid tumors

Elisabeth I. Heath, Seamus O'Reilly, Rachel Humphrey, Pavur Sundaresan, Ross C. Donehower, Susan Sartorius, John M. Kennedy, Deborah K. Armstrong, Michael A. Carducci, Mel J. Sorensen, Karen Kumor, Se

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2001

Language:

english

File:

PDF, 90 KB

english, 2001

19

Bioavailablility of penclomedine and systemic exposure to 4-O-demethylpenclomedine in patients receiving oral and intravenous penclomedine

Seamus O'Reilly, Neil R. Hartman, Katherine M. Bowling, Eric K. Rowinsky, Ross C. Donehower, Jerry Collins, John M. Strong

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2001

Language:

english

File:

PDF, 119 KB

english, 2001

20

A Phase I study of the oral antimetabolite, CS-682, administered once daily 5 days per week in patients with refractory solid tumor malignancies

Jill Gilbert, Michael A. Carducci, Sharyn D. Baker, Elizabeth C. Dees, Ross Donehower

Journal:

Investigational New Drugs

Year:

2006

Language:

english

File:

PDF, 287 KB

english, 2006

21

Thymidylate synthase (TYMS) enhancer region genotype-directed phase II trial of oral capecitabine for 2nd line treatment of advanced pancreatic cancer

Colin D. Weekes, Sujatha Nallapareddy, Michelle A. Rudek, Alexis Norris-Kirby, Daniel Laheru, Antonio Jimeno, Ross C. Donehower, Kathleen M. Murphy, Manuel Hidalgo, Sharyn D. Baker, Wells A. Messersmi

Journal:

Investigational New Drugs

Year:

2011

Language:

english

File:

PDF, 187 KB

english, 2011

22

Evolving therapies: Farnesyltransferase inhibitors

W. Thomas Purcell, Ross C. Donehower

Journal:

Current Oncology Reports

Year:

2002

Language:

english

File:

PDF, 530 KB

english, 2002

23

Phase II Study of 4-Ipomeanol, a Naturally Occurring Alkylating Furan, in Patients with Advanced Hepatocellular Carcinoma

Shailendra Lakhanpal, Ross C. Donehower, Eric K. Rowinsky

Journal:

Investigational New Drugs

Year:

2001

Language:

english

File:

PDF, 68 KB

english, 2001

24

A Phase I and Pharmacologic Study of Pyrazoloacridine and Cisplatin in Patients with Advanced Cancer

E. Claire Dees, Eric K. Rowinsky, Dennis A. Noe, Seamus O'Reilly, Alex A. Adjei, Kathy Elza-Brown, Ross C. Donehower

Journal:

Investigational New Drugs

Year:

2003

Language:

english

File:

PDF, 109 KB

english, 2003

25

Sequence-dependent cytotoxic effects due to combinations of cisplatin and the antimicrotubule agents taxol and vincristine

Eric K. Rowinsky, Martin J. Citardi, Dennis A. Noe, Ross C. Donehower

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

1993

Language:

english

File:

PDF, 809 KB

english, 1993

26

Combined effects of methotrexate and 5-fluoropyrimidine on human breast cancer cells in serum-free culture

Ross C. Donehower, Joseph C. Allegra, Marc E. Lippman, Bruce A. Chabner

Journal:

European Journal of Cancer (1965)

Year:

1965

Language:

english

File:

PDF, 587 KB

english, 1965

27

Temozolomide in Patients with Advanced Cancer: Phase I and Pharmacokinetic Study

Dr. Michelle A. Rudek, Dr. Ross C. Donehower, Dr. Paul Statkevich, Dr. Vijay K. Batra, Dr. David L. Cutler, Dr. Sharyn D. Baker

Journal:

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

Year:

2004

Language:

english

File:

PDF, 189 KB

english, 2004

28

Paclitaxel (Taxol)

Wood, Alastair J.J., Rowinsky, Eric K., Donehower, Ross C.

Journal:

Boston Medical and Surgical Journal

Year:

1995

Language:

english

File:

PDF, 172 KB

english, 1995

29

Phase I study of continuous weekly dosing of dimethylamino benzoylphenylurea (BPU) in patients with solid tumours

Wells A. Messersmith, Michelle A. Rudek, Sharyn D. Baker, Ming Zhao, Connie Collins, A. Dimitrios Colevas, Ross C. Donehower, Michael A. Carducci, Antonio C. Wolff

Journal:

European Journal of Cancer

Year:

2007

Language:

english

File:

PDF, 167 KB

english, 2007

30

Laparoscopic retroperitoneal lymph node dissection for clinical stage I nonseminomatous germ cell testicular tumors

Joel B Nelson, Roland N Chen, Jay T Bishoff, William K Oh, Philip W Kantoff, Ross C Donehower, Louis R Kavoussi

Journal:

Year:

1999

Language:

english

File:

PDF, 124 KB

english, 1999

31

Phase I dose-escalation study to examine the safety and tolerability of LY2603618, a checkpoint 1 kinase inhibitor, administered 1 day after pemetrexed 500

Glen J. Weiss, Ross C. Donehower, Tara Iyengar, Ramesh K. Ramanathan, Karen Lewandowski, Eric Westin, Karla Hurt, Scott M. Hynes, Stephen P. Anthony, Scott McKane

Journal:

Investigational New Drugs

Year:

2013

Language:

english

File:

PDF, 275 KB

english, 2013

32

Integrated preclinical and clinical development of S-trans, trans-farnesylthiosalicylic acid (FTS, Salirasib) in pancreatic cancer

Daniel Laheru, Preeti Shah, N. V. Rajeshkumar, Florencia McAllister, Gretchen Taylor, Howard Goldsweig, Dung T. Le, Ross Donehower, Antonio Jimeno, Sheila Linden, Ming Zhao, Dongweon Song, Michelle A.

Journal:

Investigational New Drugs

Year:

2012

Language:

english

File:

PDF, 384 KB

english, 2012

33

The clinical pharmacology and use of antimicrotubule agents in cancer chemotherapeutics

Eric K. Rowinsky, Ross C. Donehower

Journal:

Pharmacology & Therapeutics

Year:

1991

Language:

english

File:

PDF, 5.37 MB

english, 1991

34

Adjuvant chemoradiation versus surgery alone for adenocarcinoma of the ampulla of Vater

Jessica Zhou, Charles C. Hsu, Jordan M. Winter, Timothy M. Pawlik, Daniel Laheru, Michael A. Hughes, Ross Donehower, Christopher Wolfgang, Umer Akbar, Richard Schulick, John Cameron, Joseph M. Herman

Journal:

Radiotherapy and Oncology

Year:

2009

Language:

english

File:

PDF, 194 KB

english, 2009

35

New developments on the mechanisms of action of antineoplastic drugs

Ross C. Donehower, Charles E. Myers, Bruce A. Chabner

Journal:

Year:

1979

Language:

english

File:

PDF, 802 KB

english, 1979

36

Solitary, isolated metastasis from Ewing's sarcoma to the brain: Case report

Alessandro Olivi, Ross C. Donehower, Risa B. Mann, Henry Brem

Journal:

Surgical Neurology

Year:

1991

Language:

english

File:

PDF, 3.76 MB

english, 1991

37

Sequential methotrexate and 5-Fluorouracil in advanced ovarian carcinoma

Ross C. Donehower, Neil B. Rosenshein, Jacob Rotmensch, David S. Ettinger

Journal:

Gynecologic Oncology

Year:

1987

Language:

english

File:

PDF, 469 KB

english, 1987

38

The role of plasma level monitoring in cancer chemotherapy

Ross C. Donehower, Charles Erlichman

Journal:

Trends in Pharmacological Sciences

Year:

1981

Language:

english

File:

PDF, 355 KB

english, 1981

39

Factors Affecting Topotecan Sensitivity in Human Leukemia Samples

SCOTT H. KAUFMANN, STEVEN D. GORE, LOUIS LETENDRE, PHYLLIS A. SVINGEN, TIMOTHY KOTTKE, CHRISTOPHER A. BUCKWALTER, RICHARD J. JONES, LOUISE B. GROCHOW, PHILIP J. BURKE, ROSS C. DONEHOWER, ERIC K. ROWIN

Journal:

Annals of the New York Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 853 KB

english, 1996

40

Phase I Trial of Oxaliplatin, Infusional 5-Fluorouracil, and Leucovorin (FOLFOX4) With Erlotinib and Bevacizumab in Colorectal Cancer

Wells A. Messersmith, Antonio Jimeno, Heather Jacene, Ming Zhao, Piotr Kulesza, Daniel A. Laheru, Yasmin Kahn, Alexander Spira, Janet Dancey, Christine Iacobuzio-Donahue, Ross C. Donehower, Michael Ca

Journal:

Clinical Colorectal Cancer

Year:

2010

Language:

english

File:

PDF, 305 KB

english, 2010

41

Pretreatment H2receptor antagonists that differ in P450 modulation activity: comparative effects on paclitaxel clearance rates and neutropenia

William J. Slichemyer, Ross C. Donehower…

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1995

Language:

english

File:

PDF, 609 KB

english, 1995

42

Relation between age and clearance rate of nine investigational anticancer drugs from phase I pharmacokinetic data

Jane M. Borkowski, Mary Duerr, Ross C. Donehower…

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1994

Language:

english

File:

PDF, 448 KB

english, 1994

43

Incidence and prognostic impact of KRAS and BRAF mutation in patients undergoing liver surgery for colorectal metastases

Karagkounis, Georgios, Torbenson, Michael S., Daniel, Hubert D., Azad, Nilofer S., Diaz, Luis A., Donehower, Ross C., Hirose, Kenzo, Ahuja, Nita, Pawlik, Timothy M., Choti, Michael A.

Journal:

Year:

2013

Language:

english

File:

PDF, 201 KB

english, 2013

44

A Tolerability and Pharmacokinetic Study of Adjuvant Erlotinib and Capecitabine with Concurrent Radiation in Resected Pancreatic Cancer

Ma, Wen Wee, Herman, Joseph M., Jimeno, Antonio, Laheru, Daniel, Messersmith, Wells A., Wolfgang, Christopher L., Cameron, John L., Pawlik, Timothy M., Donehower, Ross C., Rudek, Michelle A., Hidalgo,

Journal:

Translational Oncology

Year:

2010

Language:

english

File:

PDF, 191 KB

english, 2010

45

THE SECTIONS.

Donehower, Ross C., Rowinsky, Eric K.

Journal:

Year:

1894

Language:

english

File:

PDF, 844 KB

english, 1894

46

An overview of experience with taxol∗ (paclitaxel) in the U.S.A

Donehower, Ross C., Rowinsky, Eric K.

Journal:

Cancer Treatment Reviews

Year:

1993

Language:

english

File:

PDF, 1.19 MB

english, 1993

47

HIV INFECTION PRESENTING AS AN UNUSUALLY LARGE PURE YOLK SAC TUMOR OF THE TESTIS

MUNVER, RAVI, DONEHOWER, ROSS C., KRONZ, JOSEPH D., POLASCIK, THOMAS J.

Journal:

The Journal of Urology

Year:

2000

Language:

english

File:

PDF, 204 KB

english, 2000

48

Correlation of Smad4 Status With Outcomes in Patients Receiving Erlotinib Combined With Adjuvant Chemoradiation and Chemotherapy After Resection for Pancreatic Adenocarcinoma

Herman, Joseph M., Fan, Katherine Y., Wild, Aaron T., Wood, Laura D., Blackford, Amanda L., Donehower, Ross C., Hidalgo, Manuel, Schulick, Richard D., Edil, Barish H., Choti, Michael A., Hruban, Ralph

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2013

Language:

english

File:

PDF, 129 KB

english, 2013

49

A Phase I Clinical Trial of Lethally Irradiated Allogeneic Pancreatic Tumor Cells Transfected with the GM-CSF Gene for the Treatment of Pancreatic Adenocarcinoma. The Johns Hopkins Oncology Center, Baltimore, Maryland

Jaffee, Elizabeth M., Abrams, Ross, Cameron, John, Donehower, Ross, Duerr, Mary, Gossett, Jeanette, Greten, Tim F., Grochow, Louise, Hruban, Ralph, Kern, Scott, Lillemoe, Keith D., O'Reilly, Seamus, P

Journal:

Human Gene Therapy

Year:

1998

Language:

english

File:

PDF, 1.93 MB

english, 1998

50

Phase I Study of Non-Replicating Autologous Tumor Cell Injections Using Cells Prepared With or Without GM-CSF Gene Transduction in Patients with Metastatic Renal Cell Carcinoma. Johns Hopkins Oncology Center, Baltimore, Maryland

Berns, Anton J. M., Clift, Shirley, Cohen, Lawrence K., Donehower, Ross C., Dranoff, Glenn, Hauda, Karen M., Jaffee, Elizabeth M., Lazenby, Audrey J., Levitsky, Hyam I., Marshall, Fray F., Mulligan, R

Journal:

Human Gene Therapy

Year:

1995

Language:

english

File:

PDF, 1.89 MB

english, 1995

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